DGG Mannequin

University Hospital of Giessen, Department of Cardiac, Paediatric Cardiac and Vascular Surgery, Vascular Surgery Section

Research location

University Hospital of Giessen, Department of Cardiac, Paediatric Cardiac and Vascular Surgery, Vascular Surgery Section
Head of the Clinic: Prof. Dr Andreas Böning

Research

Head of the Research Programme

PD Dr Johannes Kalder

PD Dr Paula Keschenau

Location
Rudolf-Buchheim-Str. 7
35392 Gießen

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Equipment

  • Basic Research Laboratory
  • Small Animal Laboratory          
  • Clinical Trials Centre   
  • Biomaterials Bank (Tissue/Serum)
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Methods

Methods 1 

  • Immunohistochemistry, ELISA (K)
  • Mitochondrial function analysis (K)
  • mRNA analysis (K)
  • Laboratory animal science (K)
  • Ussing chamber (K)
  • Speckle tracking analysis (E)
  • 16S rRNA gene amplification and sequence analysis (K)
  • Cell culture (K)
  • O2C (E)
  • HLM in vitro model (E)

Methods 2  

  • Speckle tracking analysis
  • O2C
  • HLM in vitro model
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Staff

  • 3 doctors with research projects                          
  • 1 teaching assistant                                                                
  • 10 PhD students                                             

Research focus areas

Clinical:         

Arteriosclerosis, vascular elasticity and calcification, microbiome,

biomarkers of mesenteric and renal ischaemia, long-term outcomes following endovascular aortic surgery, cardiac risk in vascular surgical procedures, mesenteric ischaemia

Basic research:              

Extracorporeal circulation and ischaemia-reperfusion of internal organs

Translational:           

Arteriosclerosis and vascular elasticity/calcification,

Extracorporeal circulation and ischaemia-reperfusion of internal organs

Contact person

PD Dr. med. Paula Keschenau

Send email

Publications

  • PD Dr J. Kalder

https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=50&term=Kalder+J&cauthor_id=36142966

  • PD Dr P.R. Keschenau

https://pubmed.ncbi.nlm.nih.gov/?term=Keschenau+P+%5Bau%5D&sort=date&size=50

 

Ongoing doctoral theses

  • Long-term results following TEVAR for type B dissections
  • Long-term results following EVAR
  • Long-term results following TEVAR for TAA
  • Evaluation of aortic arch anatomy
  • Long-term outcomes following endovascular management of aortic emergencies from the thoracic to the infrarenal aorta
  • Prospective evaluation of IFABP as a biomarker following cardiovascular procedures involving extracorporeal circulation
  • Early detection of acute kidney injury following cardiovascular procedures involving extracorporeal circulation and analysis of the association with

IFABP

  • Prospective analysis comparing the incidence of renal and mesenteric complications in patients following cardiovascular procedures using extracorporeal circulation
  • Evaluation and comparison of potential predictors of perioperative mesenteric ischaemia in cardiovascular procedures using extracorporeal circulation
  • Analysis of perioperative myocardial injury during vascular surgery and its risk factors
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